10 Things You Need to Know about Peripheral Neuropathy, the New American Epidemic

From the desk of contributor Dr. Randall C. LabrumNeuropathy Expert and Former Neuropathy Sufferer

Numbness. Prickling. Tingling. Burning. Debilitating pain in the feet, toes, and lower legs. Or in the hands, fingers and lower arms. Perhaps even in both locations. These are the most common symptoms of Peripheral Neuropathy, a vexing disorder brought on by damage to the peripheral nervous system which today affects tens of millions of Americans, and many more millions of people around the globe.

Here are 10 things you absolutely need to know about Peripheral Neuropathy.

1) The number of peripheral neuropathy sufferers just cited only reflects the tip of the iceberg. Indeed, in years to come peripheral neuropathy, which is right now increasing in prevalence at a mind-blowing rate, has the potential to become one of the most widespread scourges humanity has yet known.

2) Why be alarmed? Because peripheral neuropathy strikes individuals without pity. It strikes for a vast variety of reasons, both exotic and distressingly common-place (diabetes, aging, and high-blood pressure, for example). And if you develop neuropathy and only put your trust in contemporary medicine, you’ll be rather unapologetically told that neuropathy is virtually without cure or treatment.

3) As a result, neuropathy sufferers are usually desperate. Nothing has worked for them. The painkilling medicines generally suggested as the only real course of action by most doctors cause awful side effects. They are prescribed with the caveat that there is nothing else we can do. Indeed, in all my years of experience I have yet to meet a neuropathy patient who was completely satisfied with their progress or how the doctor was handling their case.

4) Virtually all neuropathy patients feel like orphans. As though they have nobody to turn to, nobody who truly knows how to help them, and nowhere to go with their problem. Meanwhile, the painful and frustrating symptoms continue to intensify and the feelings of being abandoned and left alone with no help grow more acute. This unpleasant situation often contributes to depression and despondency, with the neuropathy sufferer finally just giving up and doing nothing more to help his or her problem. Suffering for the remainder of their days, with an almost complete abandonment of a desired lifestyle, seems to be the only possible outcome. This is, of course, no way to live.

5) Fortunately, as a friend and neuropathy treatment coach, my message to these neuropathy sufferers is simply this: Be of good cheer! There is a solution. Click here to jump to it now .

As a previous neuropathy patient myself, I have recently published a simple, proven, step-by-step neuropathy treatment program based on my successes in resolving the peripheral neuropathy condition. In my own case, my perplexing and painful neuropathy symptoms are totally gone and my life is back on track again.

6) Many, if not most of my patients have had the same experience with my neuropathy program. It is at their request that I am making my program widely available to everyone, with the intent of helping as many of the frustrated victims of the emerging neuropathy epidemic as possible. Those who have followed the program as outlined have, without exception, achieved a measurable amount of satisfaction and improvement.

The amount of this correction and improvement is of course different in each individual case, and depends on obvious variables such as patient compliance and motivation, and on clinical factors such as general health and the severity and complexity of the underlying causes.

7) It is critically important for every neuropathy sufferer to understand that all cases of neuropathy will do better if the damaged peripheral sensory nerves in the lower legs, feet, and hands, and the environment in which they are found, can be made healthier, less toxic, and more whole. These goals are precisely what my neuropathy program is designed to help the neuropathy sufferer accomplish.

Indeed, my program is designed to help the neuropathy sufferer finally gain the upper hand in the fight against this devastating epidemic.

8) Medical schools, researchers, and neuropathy organizations estimate that between 20-30 million cases of peripheral neuropathy exist within the borders of the United States, with millions more being diagnosed each year.

Already, a full 8% of the millions of Medicare patients have peripheral neuropathy as a secondary diagnosis in their doctor provided diagnostic record. And these figures do not even speculate about the untold number of undiagnosed cases (peripheral neuropathy is still largely under the radar of many physicians and the media in general), or the millions of new developing cases whose symptoms are just beginning to manifest themselves, nor do they take into account the additional millions upon millions of peripheral neuropathy patients who live in other countries around the world.

9) By way of comparison with other so-called health epidemics, there are 400,000 people in the US with Multiple Sclerosis, 5,000,000 Americans suffer from Alzheimer’s, and roughly 250,000 people in the US will be diagnosed with breast cancer this year. As already mentioned, peripheral neuropathy is, right now, afflicting at least 20 to 30 million Americans. Even if you do not presently have peripheral neuropathy, chances are very high that at some point down the road it will affect your life either directly or indirectly.

10) If you or someone near and dear to you is currently a neuropathy sufferer, you truly owe it to yourself to explore the vital information and proven recommendations I have prepared for you in my neuropathy program. Detailed in my program you will find clear answers to perplexing questions about what exactly Peripheral Neuropathy is; why you or someone you care for has it, or why you may or may not expect to be afflicted with it in the future; and what exactly can be done to both prevent it and treat it.

My program is presented in six simple steps which anyone can easily do. Each step is explained in plain English and illustrated in clear, step-by-step detail. By employing these steps the neuropathy sufferer will enhance the health of their peripheral sensory nerves and the surrounding environment, thereby reducing the pain, numbness, tingling, and other symptoms characteristic of the condition. Measurable and usually dramatic improvement is reasonable to expect in just a short time upon following my program.

Please do not fail yourself with prejudice, doubt, indecision or lack of action.

Recovery, healing and prevention are waiting for you, but you alone must take the responsibility and fulfill the simple, easy to learn steps which lead to dramatic improvement of this frustrating condition. 

Click here to begin my neuropathy program now.

5 False Neuropathy Facts Your Doctor Mistakenly Promotes

From the desk of Dr. Randall C. Labrum, Neuropathy Expert and Former Neuropathy Sufferer

As I go from place to place giving lectures, classes and seminars on the subject of Peripheral Neuropath, an unfortunate situation continues cause me great concern. Without exception, my seminar attendees think and believe that their condition of neuropathy has no cure.

The medical community is largely responsible for this misinformation being passed on to the suffering patient. In my view it is the job and responsibility of the family doctor to teach the patient about their neuropathy problem. It is also the doctor’s job to train the patient in what they can do to improve and manage their neuropathy case successfully.

Given the misconceptions of my seminar attendees however, this teaching and training obviously isn’t being done. That this discouraging situation be allowed to continue year after year, in a world where medicine has otherwise come to offer so many outstanding solutions and even “miracles”, is a real shame.

Many neuropathy patients, suffering with foot or hand pain, tingling, numbness, burning, and other evasive and hard to describe neuropathy symptoms, don’t even know the name of their condition! And while others do, that is essentially all they know. With this in mind I want to address some of the most commonly INCORRECT “facts” that suffering neuropathy patients have been told, or come to understand, due to the lack of patient education by the medical community.

1. Neuropathy comes with age, and there is nothing you can do about it.

This statement is only partially correct, inasmuch as aging can contribute to the increased onset and intensity of the neuropathy condition. There are however, many simple techniques and procedures that any person can learn which will offset many of these effects of aging as they relate to peripheral neuropathy.

One example of the many easy things that can be done is to simply recline on the sofa for a fifteen minute nap with the feet propped up on the back of the sofa above the level of the body. This simple “exercise” allows stagnated, toxin laden blood in the feet and lower legs to move more rapidly back to the heart and lungs with the assistance of gravity, where it will be oxygenated and cleansed.

2. We do not know what causes neuropathy.

This is absolutely incorrect! Most causes of neuropathy are indeed known and not difficult to understand. Cancer patients being treated with chemotherapy, for example, are at very high risk for developing neuropathy. The poisonous effects of the powerful cancer killing drugs are known to damage the sensory nerves in the feet, hands and other peripheral areas. Diabetes is an obvious and well-known catalyst for peripheral neuropathy as well. A lesser known example is the sudden reduction of blood pressure due to anti-hypertensive prescriptions, which is nonetheless perhaps one of neuropathy’s leading causes.

Since neither surgery nor prescription drugs are effective at curing peripheral neuropathy, most physicians are not willing to take the time to educate and manage these types of cases and will instead simply tell the patient that there is no known cause or cure, and that the best that can be offered are powerful, painkilling drugs. This is truly an unfortunate and incorrect approach to a very treatable condition.

3. There are no treatment procedures for neuropathy.

In reality the best treatment procedures for peripheral neuropathy do not need to be administered by a doctor. Therefore the doctor is neither motivated to learn them nor teach to the patient. Experience has proven that most family doctors are not even aware of these methods and are not motivated to get involved with this type of patient management; this is because it is too time intensive and not worthwhile financially. Patients must therefore assume the responsibility of learning and implementing the methods of self-treatment. I have created a simple step-by-step program that will teach you these methods which you can get at this link.

This is actually a good and positive thing! Significant amounts of money will be saved by the patient taking over their own case and not paying the high professional fees. By reducing these costs, most any person is able to correct their neuropathy problem without the financial burdens that prevent many individuals from getting the care which they otherwise need and deserve.

4. Neuropathy just gets worse with time, and you have to accept that you are stuck with it.

This statement is only true if the neuropathy patient ignores their condition and takes no remedial action. If corrective, self-treatment procedures are implemented by the patient, the miserable symptoms of neuropathy can be greatly improved. Instead of the condition worsening and an individual finding himself stuck with it, life gets much better as the pain, numbness, and tingling sensations get better and normal life returns. This is made possible as the sufferer begins taking easy and proven steps which I reveal in my neuropathy program for improving the circulation in the legs and feet.

5. Since you are diabetic, there is no help available for you.

This very incorrect but common statement is so unfortunate and untrue. Although the condition of diabetes does indeed complicate the condition of neuropathy, it does not eliminate the diabetic patient from significant help with their neuropathy condition. Most persons with severe diabetic neuropathy would be very satisfied with 30-70% improvement of their condition. This is what we have experienced by teaching diabetic individuals how to increase circulation and regenerate the health of their sensory nerves in the legs, feet, and hands.

In terms of all of the misconceptions I’ve just addressed, it is ultimately the responsibility of the neuropathy sufferer to prove them incorrect for himself, by acquiring the information and education necessary to start the healing process on his own. A doctor likely won’t hold your hand through this process, nor even point you in the right general direction. Unfortunately, that’s just not the way the system as it is set up today works.

Please do not fail yourself with prejudice, doubt, indecision, or lack of action. Recovery is waiting for you, but you alone must take the responsibility and fulfill the simple, easy to learn steps which lead to dramatic improvement of this frustrating condition.

For more information on how you can began taking charge of your neuropathy condition as soon as today, I invite you to review the special, highly effective resolution program I created uniquely for peripheral neuropathy sufferers. You can Click Here  to go directly to the program’s website now.

Diabetics and Exercise

Importance of Physical Exercise For Diabetes Patients

Diabetics and Exercise

The importance of exercise and physical activity has been proven time and time again in a multitude of studies over the past few decades. For diabetics, exercising has been shown to be just as important as having a healthy and nutritious diet to maintain healthy blood sugar levels.

Even in healthy individuals, exercise helps improve blood circulation, prevents a build-up of plaque and helps oxygenate the blood, keeping the heart, vessels and the entire body healthy. Since diabetics face higher chances of cardiovascular diseases compared to other people, regular and vigorous physical activity is a crucial part to effectively reduce that risk.

Can exercise be effective in curbing or even curing diabetes?

When it comes to type 2 diabetes, the importance of exercise cannot be understated. Vigorous exercising can help you fight diabetes in several important ways:

1.Exercising helps deplete glycogen from your muscles (energy storing form of glucose) which lowers your overall sugar levels

and

2. Exercise increases your overall muscle mass, which creates more space for your body to store excess sugar properly, effectively and without harm to your body.

Thus, in the case of type 2 diabetes, exercise can help greatly improve your state and potentially – eventually! – even help cure diabetes. However, this will not be the case with type 1 diabetes or even type 2 diabetes not caused by insulin resistance.

Things to know about exercising with diabetes

Timing

If you are a busy person, it is a very good idea to exercise at any time of day, whenever you can find the time for it. However, for better results, you should avoid exercising early in the mornings before your first meal. Very often people believe that exercising before eating can lead to the body using stored fat and thus weight loss. Some even believe that it’s a good way to keep blood glucose lower while exercising and throughout the day.

However, early morning exercises may be detrimental to blood glucose levels control.

Many diabetes doctors advise avoiding exercising first thing in the morning before you have your breakfast. This is because, if you haven’t yet eaten and start to vigorously exercise, your body may increase the release of glucose-raising hormones to help fuel your activity. Instead of lowering your blood glucose levels for the day, it will actually raise them! To prevent a spike in blood glucose levels, try to exercise after a meal, never before.

How much to exercise

The correct answer is as much as you can within the norm prescribed by your doctor. Generally, 2 – 2.5 hrs per week is considered ideal. By exercising this much, you should be able to significantly lower your A1C levels within a few months (for people with Type 2 diabetes). For people with type 1 diabetes, the correlation isn’t as evident, but exercising is beneficial for overall body health in any case.

What type of exercising is best for diabetes?

Both cardiovascular and strength training exercises help lower blood sugar levels allowing a balanced and healthy glycemic level. However, while any exercise is better than none, if you are looking into losing some weight and better controlling your diabetes, you should pay greater attention to anaerobic exercise as opposed to aerobic exercises.

Some of the examples of anaerobic exercises are heavy weight lifting, hill climbing, interval training and other types of weight and resistance-related exercises. Aerobic exercises are such exercises as treadmill exercising, swimming, running, dancing, aerobics classes etc. Anaerobic exercises are great for diabetes patients because they tend to increase muscle mass. Most of the body glucose is stored in the muscles, and the more you have, the more productively the glucose will be stored and used for performance as opposed to harming your body. Regular exercise will also help you achieve a toned body and more defined muscles. Regular exercise increases muscle mass in the body, which in turn makes it more effective in burning fats. This will make you lean and strong, and help you deal with any extra weight you may have.  With excess weight gone, you will experience less pressure on the joints, significantly lowering the risks of joint problems.

A lot of people, particularly those who live a sedentary lifestyle, might have a hard time starting to follow a regular exercise program. Patience is key! Try to slowly incorporate the exercise program into a daily routine, and don’t give up if it takes time and effort.  Make sure to avoid rushing anything and exerting too much as it may pose a risk such of injury or your overall health getting worse instead of better. Exercise is great for everyone, including and especially for diabetes patients. However, as with everything, it is important to monitor your health and overall state and consult with your physician if you notice any signs of pain, discomfort or any other unusual symptoms while or after exercising.

Regular exercise will also help you burn more body fat. Exercise that is more constant trains the muscles, making the body burn more fats easily. Without excess fats in the body, there will be less pressure on the joints, significantly lowering the risks of joint problems and less strain on the muscles as there is no need to exert more strength in carrying a heavy body.

 

If you are suffering from diabetes-related neuropathy, please check out this Guide by Dr. Randall C. Labrum, Clinician, Researcher and Author. It has helped a lot of people end chronic peripheral neuropathy and regain health and well-being.

“I get so excited every time I have the opportunity to help someone with a chronic unresolved health problem. The ability to provide my expertise and experience in resolving these conditions creates a feeling of satisfaction like nothing else.”
Dr. Randall C. Labrum, Clinician, Researcher and Author

 

Disclaimer of Medical Liability

This site is not designed to, and does not: provide medical advice, professional diagnosis, opinion, treatment, or services to you or to any other individual. Through this site and links to other sites, Metformin Facts provides general information for educational purposes only.

The information provided in this site, or through links to other sites, is not a substitute for medical or professional care, and you should not use the information in place of a visit, call, consultation or the advice of your physician or another healthcare provider. Metformin Facts is not liable or responsible for any advice, course of treatment, diagnosis or any other information, services, or product you obtain through this site.

Metformin and vitamin B12 deficiency

Vitamin B12 Deficiency and Diabetes

Vitamin B12 Deficiency Among Diabetic PATIENTS

As you probably already know, one of the side effects of metformin is that it prevents proper nutrient absorption from food in your intestinal tract. Vitally important vitamins and minerals pass through your system not absorbed, leaving your body deficient in the elements it needs to rebuild and heal itself. As you can understand, it’s a dangerous side effect, in that it can further exacerbate your condition and weaken your body even more, although all you are trying to do is to actually help it fight the disease.

The solution to this side effect is to start supplementing your diet with vitamins and minerals to maintain the proper balance in your body and to help your body acquire those building blocks that it needs for its perfect performance. I definitely recommend speaking to your doctor about supplementation. It is possible that they will have you do some tests to see what you may already be deficient in and recommend certain supplements to support you.

Although supplements have been thoroughly researched and a multitude of studies have proved them effective and safe, a lot of people are still skeptical about the idea of nutritionally supplementing their diet, whether they are diagnosed with Type 2 diabetes or not. You may think you are already eating a healthy and balanced diet. Why would you need to supplement?

A harsh truth is that only a few of us come close to eating a truly healthy and balanced diet, even those that aren’t on metformin. The type of lifestyle people live today contributes to the decreasing quality of the food we eat. Our soil is depleted of nutrients due to constant overuse. Our meat, instead of being grass-fed, is often fed grains and other foods that aren’t nutritionally rich, and so we can’t get the nutrition we should be able to get from meats. In addition to that, most people simply don’t have a diverse and rich enough diet to really enjoy the nutritional variety that we need to thrive. A lot of us eat out in fast foods restaurants almost daily, and even if you eat at home, it is possible that most of your food is nutritionally poor processed food. These type of foods undoubtedly lack in nutrients needed by the body for proper function and performance.

Another misconception is the idea that supplements are really not that beneficial and are only a waste of money. This could not be farther from the truth! You will be surprised how much difference even a single supplement can make in your everyday life. I can attest to a major improvement in my health state after I began taking vitamins B6, B12, vitamin D, and iron. For my particular case, those were an absolute game changer. It is always a great idea to check your vitamin and mineral levels professionally to get a better picture of how your body is doing, especially if you are on such harsh medication as metformin. Further in this article, I will concentrate more on Vitamin B12 in particular as one of the most vitally important vitamins for your body to thrive.

BENEFITS OF VITAMIN B12

Vitamin B12 is one of the water-soluble vitamins that provides the following benefits:

  • Effective metabolism of protein, carbohydrates, and fat
  • Improves the function of iron in the body
  • Supports proper maintenance of a healthy central nervous system
  • Supports healthy folate activity and calcium absorption
  • Helps increase your energy
  • Helps in healthy formation and regeneration of red blood cells.

Here is some of my personal history with vitamin B12. At a certain point, I noticed that I started forgetting words, and it took me a while to remember them while speaking. I also noticed I became mentally slow. I talked slowly, I constantly stammered and couldn’t find words for even the simplest concepts. I couldn’t even think fast. I lived in a nearly constant state of mental fog. Then I found out I was deficient in Vitamin B12.

I started taking supplements, just one tablet a day, and the results have been short of amazing. I noticed that I am much less tired. I think and speak faster and make decisions with greater ease. I have much more energy. And that’s just what I see on the surface. I am sure if I did some tests, I would see some great results in the internal systems of my body as well. This is why I highly recommend supplementing with B12, especially if you are on metformin which tends to exacerbate malabsorption of nutrients and may wreak havoc in multiple systems of your body unless you help support yourself.

Through diet, Vitamin B12 can be obtained by consuming tuna, salmon, chicken, milk, and eggs, and also vegan burger patties fortified with Vitamin B12. You can see that most of the sources of B12 are of animal origin, so if you are a vegetarian or especially vegan, you are almost 100% guaranteed to be lacking in vitamin B12.

A study that involved 46 individuals diagnosed with Type 2 Diabetes and taking either Metformin or Phenformin or both, showed that thirty percent of patients had vitamin strong B12 malabsorption. This meant that their bodies had difficulties in absorbing the vitamin, which resulted in the deficiency that continued even when the intake of medications was stopped. This is quite a large percentage of such a small representative group. In reality, almost anyone should supplement with vitamin B12, even if they aren’t on metformin.

Symptoms of vitamin B12 deficiency

How can you tell if you are vitamin B12 deficient?  The best way is to do medical tests to find out. However, some of the signs of vitamin B12 deficiency include the following:

  • weakness and/or soreness in arms and legs
  • slow sensory perception and reflexes
  • stammering and nervousness
  • jerking in limbs and difficulty walking
  • inflammation of the nerves
  • memory loss and mental slowness
  • mood disorders (irritability, depression, anger, etc..)
  • unpleasant body odor

Your health care provider can easily monitor your vitamin B12 levels through a blood test. In the case of severe deficiency, your doctor can administer vitamin B12 injections under the tongue or by using a patch that can quickly deliver the vitamin to the body. Once your levels are stabilized, you can maintain healthy levels of daily Vitamin B12 supplementation.

If you are suffering from diabetes-related neuropathy, please check out this Guide by Dr. Randall C. Labrum, Clinician, Researcher and Author. It has helped a lot of people end chronic peripheral neuropathy and regain health and well-being.

“I get so excited every time I have the opportunity to help someone with a chronic unresolved health problem. The ability to provide my expertise and experience in resolving these conditions creates a feeling of satisfaction like nothing else.”
Dr. Randall C. Labrum, Clinician, Researcher and Author

 

 

Disclaimer of Medical Liability

This site is not designed to, and does not: provide medical advice, professional diagnosis, opinion, treatment, or services to you or to any other individual. Through this site and links to other sites, Metformin Facts provides general information for educational purposes only.

The information provided in this site, or through links to other sites, is not a substitute for medical or professional care, and you should not use the information in place of a visit, call, consultation or the advice of your physician or another healthcare provider. Metformin Facts is not liable or responsible for any advice, course of treatment, diagnosis or any other information, services, or product you obtain through this site.

Diabetes and Heart Disease

Diabetes and The Risk of Heart Failure

Can Diabetes Lead to Heart problems?

One of the possibly fatal complications that can be caused by Type 2 Diabetes is diabetic heart disease. Patients with diabetes are much more predisposed to heart disease than other individuals. They have additional causes that can lead to heart disease, they can get it at younger ages, in more severe forms, and their systems are already weakened by diabetes to effectively prevent or curb heart issues. Diabetics can experience such heart diseases as diabetic cardiomyopathy, coronary heart disease, and heart failure.

Causes of heart disease in diabetic patients

One of the main reasons for heart disease in type 2 diabetes patients is insulin resistance. Insulin resistance tends to cause blood clotting, which over time can lead to blocked coronary arteries. This poses a serious risk of a heart attack and can be lethal.

Metabolic syndrome is another risk factor for heart disease. Metabolic syndrome is very common for diabetes sufferers and can be described as a combination of several or all of the following: high bad cholesterol and low good cholesterol (HDL) in your system; high blood pressure, high blood sugar; increased waistline and some others.

High blood pressure and high sugar levels may lead to atherosclerosis (build-up of plaque in the arteries) in diabetic patients, which is another risk factor for heart disease.

The number and graveness of risk factors and their consequences in the form of heart disease, of course, is a major source of concern both for a diabetic patient and their family.

However, you can be proactive and take measures to maintain and strengthen your health and prevent any possible heart complications. A change in lifestyle, diet, and level of activity may help better control diabetes and its complications. Staying on top of prescribed medications can be also vitally important.

METFORMIN AND HEART DISEASE IN DIABETIC PATIENTS

Metformin will often be the drug of choice for the pre-treatment and the treatment of Type 2 Diabetes with the purpose of controlling the disease itself and its possible complications. The journal Circulation and Heart Failure recently published an article about how Metformin is able to also prevent death from heart disease caused by diabetes.

A study conducted at Baylor College of Medicine by researchers and Michael E. De Bakey of VA Medical Center in Houston, Texas, involved 6,185 Type 2 Diabetes patients who had heart failure. Twenty-five percent of these patients were treated with Metformin. The research concluded with the following results:

  • After a two-year period, 15.8% or 246 patients who were treated with Metformin died.
  • After a two-year period, 25.5% or 1177 patients who were not treated with Metformin died.

Both of the groups that were part of the research had the same total rate of hospitalization due to heart failure as well as the rate of hospitalization. However, diabetic patients with heart failures that have undergone Metformin treatment had a higher chance of survival. The study concluded with the need for more related studies in order to discover effective therapies for patients that are diagnosed with both Type 2 Diabetes and heart failure.

Metformin belongs to a family of drugs known as biguanides (the blood sugar controlling drugs). It is one of the insulin-sensitizing drugs, that helps prevent the fluctuation of glucose between meals allowing effective weight loss. It also limits the total amount of insulin that comes from the pancreas instead of increasing it and controls the amount of glucose coming from the small intestines and liver that enters the blood flow.

Type 2 Diabetes is known to promote insulin resistance. Biguanides like Metformin attack the disease at the root. In general, Metformin is a safe medication. However, it has a range of side effects. For example, there are rare instances where patients who take the drug develop lactic acidosis, which is a serious condition. Ten to Thirty percent of Metformin users report that they experience gastrointestinal side effects, which subside over time. If you experience a similar side effect that does stay long, you can consult your doctor for the administration of a lower dose. Metformin is also known as Glucophage, Glumetza, or Fortamet in the market. These are brand names of Metformin with slightly different formulations, and they tend to cause fewer side effects.

Metformin should be taken regularly to be able to achieve its positive effects. However, there are some instances where its use should be discontinued temporarily. If you are suffering from severe diarrhea, fever, vomiting, in need of less than normal fluid intake, you should alert your doctor immediately. If you are undergoing X-ray procedures, you should also let your doctor know or ask beforehand if using Metformin when undergoing an X-ray scan is advisable.

Metformin is a popular choice to control diabetes and its possible complication in the form of heart disease as it is generically available and is cheaper than most drugs available. However, don’t forget to also pay attention to your lifestyle, your exercise regime, nutritional supplementation, and diet. All of these factors will greatly improve your chances to live healthier and happier!

If you are suffering from diabetes-related neuropathy, please check out this Guide by Dr. Randall C. Labrum, Clinician, Researcher and Author. It has helped a lot of people end chronic peripheral neuropathy and regain health and well-being.

“I get so excited every time I have the opportunity to help someone with a chronic unresolved health problem. The ability to provide my expertise and experience in resolving these conditions creates a feeling of satisfaction like nothing else.”
Dr. Randall C. Labrum, Clinician, Researcher and Author

 

Disclaimer of Medical Liability

This site is not designed to, and does not: provide medical advice, professional diagnosis, opinion, treatment, or services to you or to any other individual. Through this site and links to other sites, Metformin Facts provides general information for educational purposes only.

The information provided in this site, or through links to other sites, is not a substitute for medical or professional care, and you should not use the information in place of a visit, call, consultation or the advice of your physician or another healthcare provider. Metformin Facts is not liable or responsible for any advice, course of treatment, diagnosis or any other information, services, or product you obtain through this site.

Metformin, diabetes and food interactions

Metformin Food Interactions

How Does Metformin And Other Anti Diabetic Drugs Interact With Food?

When you are taking any medication, it’s important to know what other life factors can affect that medication’s absorption and functioning in your body. Food is one of the most important factors to take into consideration. Consumption of alcohol is another.

Many types of foods, especially those that originate from plants, have various chemical compounds that interact with the enzymes present in the liver. These enzymes are also used by the liver to destroy and detoxify active chemicals that are present in the medications you take to control diabetes. It is important to know how the type of food you consume will affect your liver’s ability to recycle the active ingredients present in diabetes medications, as well as which type of foods can slow this process down as these will affect the rise and the dip of blood sugar levels.

How foods affect diabetic drug processing

How the food you eat will affect the diabetes medication you take will depend on what enzyme is used by your liver to break down those medications. This is an overview of how several known diabetic drugs are processed in the liver and how they are affected by the foods you eat.

Metformin

Also known as Glucophage, metformin is one medication that does not get processed by the liver. This means the use of Metformin cannot be affected by the food you eat.

However, consumption of alcohol does affect metformin metabolism. Excessive alcohol in your system will lead to metformin breaking down too much lactate which can cause one of the metformin side effects known as lactic acidosis. It’s a serious condition that is characterized by an increased amount of lactate in the body and can cause multiple negative symptoms such as trouble breathing, weakness, diarrhea, vomiting, abdominal pain, muscle pain, and tiredness. In severe cases, lactic acidosis can be lethal. To avoid any negative symptoms, it is best to avoid alcohol or limit it to very small amounts ( 1 drink a day maximum for women and 1-2 for men) while medicating with metformin. You will be even better off speaking to your doctor about risks of consuming alcohol in your particular case as well.

Vildagliptin

Also known as Galvus, vildagliptin is a diabetes medication that is processed by the liver with cytochrome P450. However, the processing is very limited. Through consuming licorice, grapefruit, ginger, or hot peppers, you can increase the ability of this medication to decrease blood sugar levels in the body.

Sitagliptin

Also known as Januvia, sitagliptin gets processed in the liver with the CYP2C8 and CYP3A4 enzymes. Avoid eating too much fruit and drinking fruit juices as these will interfere with the enzymes and increase the possibility of more severe side effects caused by the medication. When using Sitagliptin, you should particularly avoid consumption of mangoes, oranges, dragon fruits, rambutans, passion fruits, pawpaws, wild grapes, pomegranates, wild mulberries, and kiwis.

Pioglitazone

This medication is also known as Actos and is processed with the CYP2C8 enzyme. All of the fruits mentioned above (mangoes, oranges, dragon fruits, rambutans, passion fruits, pawpaws, wild grapes, pomegranates, wild mulberries, and kiwis) will also affect this medication so it is important to avoid them especially pomegranate juice.

Rosiglitazone

The CYP2C8 enzyme also processes Rosiglitazone, also known as Avandia, so it is also advised to avoid the fruits mentioned earlier. The intake of pomegranate juice will also cause this medication to produce greater side effects so stay away from the fruit juice as much as possible.

Food is very important when it comes to maintaining your body’s ideal health and well-being. Maintaining a correct diet and supplementing vitamins and minerals, as well as watching foods that can affect your medications should be high on your list of priorities in your quest to feel better.

Another important factor is following a healthy lifestyle, which includes: eating the right amount of healthy foods, maintaining regular physical activity and reducing stress.

If you are suffering from diabetes-related neuropathy, please check out this Guide by Dr. Randall C. Labrum, Clinician, Researcher and Author. It has helped a lot of people end chronic peripheral neuropathy and regain health and well-being.

“I get so excited every time I have the opportunity to help someone with a chronic unresolved health problem. The ability to provide my expertise and experience in resolving these conditions creates a feeling of satisfaction like nothing else.”
Dr. Randall C. Labrum, Clinician, Researcher and Author

 

Disclaimer of Medical Liability

This site is not designed to, and does not: provide medical advice, professional diagnosis, opinion, treatment, or services to you or to any other individual. Through this site and links to other sites, Metformin Facts provides general information for educational purposes only.

The information provided in this site, or through links to other sites, is not a substitute for medical or professional care, and you should not use the information in place of a visit, call, consultation or the advice of your physician or another healthcare provider. Metformin Facts is not liable or responsible for any advice, course of treatment, diagnosis or any other information, services, or product you obtain through this site.

DIABETES AND HEART ATTACKS

Diabetes, Heart Attacks and Metformin

How do heart attack survivors respond to Metformin?

Cardio-vascular diseases are a reason behind more than half of all deaths in diabetic patients. Heart attacks – fatal and not fatal – are fairly common in diabetics. Metformin, a common drug for type 2  diabetes, has been shown to be very effective not only in preventing the development of heart disease but also after a heart attack has already occurred in diabetic patients.

A study conducted in the Cardiology Unit of the Department of Medicine, Karolinska Institute in Sweden involved a group of researchers that aimed to discover how heart attack survivors that were diagnosed with diabetes respond to different types of treatments, including metformin. In February 2011, the results of their findings were published in a journal named Diabetologia.

The subject of the study were 1,145 patients that were diagnosed with Type 2 Diabetes and had also suffered and survived a heart attack. These patients were divided into three different groups.

  1. The first group was administered with insulin
  2. The second group was administered with metformin along with conventional treatment
  3. The third group was only provided with conventional treatment for 2.1 years

All of the patients were monitored for an average of 4.1 years. The study indicated that the number of fatal heart attacks during the monitoring period was the same in the three groups. However, non-fatal heart attack rates differed. The highest rate of heart attacks that were non-fatal was in the group treated with insulin. The group who received conventional treatment had the lowest risk in death from cancer while the group that was administered with Metformin both had low risks in death from heart attack and from cancer compared to the other patients from the other groups.

A more recent set of studies researched the mechanisms by which metformin is able to curb heart disease and help patients heal after heart attacks. The scientists from Newcastle University, Saudi Arabia, were able to create a model of a heart attack in the lab conditions. They were able to monitor the formation of the new blood vessels which is essential for the recovery after heart attack. They were also able to see that metformin enhanced the process of those blood vessels formation. Metformin has been shown to be able to lower blood glucose in the heart attack model, which is one of the factors that hinders new vessel formation. Metformin also was shown to activate a set of genes that help strengthen the new vessels and thus lead to a faster and more effective recovery.

This outcome is very promising not only in terms of using metformin to help diabetic patients who have survived heart attacks but also in developing new drugs aimed specifically at healing after heart attacks in a wider population.

Metformin, which is available in tablet form and is commonly known as Fortamet, Glucophage, or Glucophage CR is used to lower blood sugar levels. Individuals diagnosed with Type 2 Diabetes commonly use it and it can also be used to prevent the development of Type 2 Diabetes for pre-diabetic patients. A Canadian study showed that the use of both Avandia and Metformin helped decrease the risk of diabetes in pre-diabetic volunteers.

If you are suffering from diabetes-related neuropathy, please check out this Guide by Dr. Randall C. Labrum, Clinician, Researcher and Author. It has helped a lot of people end chronic peripheral neuropathy and regain health and well-being.

“I get so excited every time I have the opportunity to help someone with a chronic unresolved health problem. The ability to provide my expertise and experience in resolving these conditions creates a feeling of satisfaction like nothing else.”
Dr. Randall C. Labrum, Clinician, Researcher and Author

 

Disclaimer of Medical Liability

This site is not designed to, and does not: provide medical advice, professional diagnosis, opinion, treatment, or services to you or to any other individual. Through this site and links to other sites, Metformin Facts provides general information for educational purposes only.

The information provided in this site, or through links to other sites, is not a substitute for medical or professional care, and you should not use the information in place of a visit, call, consultation or the advice of your physician or another healthcare provider. Metformin Facts is not liable or responsible for any advice, course of treatment, diagnosis or any other information, services, or product you obtain through this site.

DIABETES AND ARTIFICIAL SWEETENERS

Diabetes And Artificial Sweeteners

Diabetes And Artificial Sweeteners – Are They Really As Good As They Say?

If you have Type 2 Diabetes, it is very important to take extra caution in controlling the amount of sugar you intake with your meals. Your dietitian or doctor will often instruct you to cut down your sugar and carbohydrate intake. Of course, this may often require great discipline, especially if you have a sweet tooth. Good news is, there is already a wide variety of artificial sweeteners available on the market. But finding the best ones among the multitude of sweeteners available can be very confusing. Here is a little overview of what artificial sweeteners are and which ones you can use safely in your meals.

WHAT ARE ARTIFICIAL SWEETENERS?

Artificial sweeteners, also known as artificial sugars, are food additives that do not contain sugar but taste like sugar. Artificial sweeteners are usually sugar substitutes that were not derived from natural sources but produced artificially. For example, one of the most popular and commonly used artificial sweeteners is sucralose. Artificial sweeteners are a popular alternative or substitute for sugar as they contain little to no calories. In the diabetic world, they are used because they provide sweetness without harming your blood sugar levels. The sweeteners are also harder for your body to break down and process, so in many cases, they easily pass the intestinal tract as is, without adding to your calorie load or causing a spike in insulin. (This is not the case for aspartame, however.) Artificial sweeteners are generally sweeter than sugar, although some sweeteners often leave a bitter aftertaste, which is tolerable for some but can be bothersome for others.

Artificial sweeteners are commonly used by manufacturers of products that cater to diabetics and those who are conscious about their weight and the type of food they are eating.

ARTIFICIAL SWEETENERS ON THE MARKET

Aspartame

Aspartame is an artificial non-saccharide sweetener invented in the 1980s. It was commonly known through its popular brand names such as Spoonfuls, Sweetmate, and Equal. Aspartame is derived from amino-acids and it is metabolized and digested by the body just like food containing protein. Aspartame is about 200 times sweeter than sugar so only a tiny amount of this sweetener can satisfy your sweet cravings. Although aspartame comes very close to sugar in its taste profile, the taste still differs significantly in how it affects your receptors and how long it lasts.

Aspartame can be found in various types of products such as desserts, different kinds of snack foods, gums and candies, salad dressings, beverages, and breakfast cereals. Because of the way it breaks down, aspartame is not a good sweetener for baking and does not support a long shelf life of a product.

Aspartame is one of the most thoroughly tested food additives on the market. It is currently considered safe, although some studies disproved its effectiveness of use for diabetics and in weight loss. Some studies have associated aspartame with weight gain and heart disease risks. Do consult your doctor before using aspartame in your diet.

Sucralose

Another known sweetener is Sucralose, which is also popularly known as Splenda. It is known to be 600 times sweeter than sugar and is in a crystalline powder form made from sugar. Sucralose cannot be absorbed by the body’s digestive tract so has zero calories. It also does not promote dental cavities. Sucralose or Splenda can be found in most packaged foods, baked goods, frozen foods, and hot or cold foods. It is considered safe to use for diabetics, although a 2018 study has shown that non-caloric (zero calories) sweeteners may be associated with weight gain as opposed to weight loss. Another study conducted by the Journal of Toxicology and Environmental Health (2008) showed that sucralose may alter the intestinal bacterial environment in your body, increasing your risks of gastrointestinal infections caused by the infiltration of pathogenic microorganisms. There are also reported cases of artificial sweeteners such as Splenda causing drug interactions (also according to the study conducted by the Journal of Toxicology and Environmental Health.) Further research is needed to specify this finding.

Pay attention

While cooking or consuming foods with artificial sweeteners, you should also take in consideration the fact that most of the foods where artificial sweeteners are used will still contain calories. It is true that the sweeteners themselves contain zero calories but the rest of the ingredients present in the food you eat will still contain some calories. Make sure to take special precautions and continue to monitor your caloric intake to be sure.

CONCLUSION

Although the above-mentioned artificial sweeteners have been approved by FDA and are easily available on the market, my recommendation is that they should only be used to satisfy your cravings for something sweet – occasionally! Not every day. Health experts still advise that these sweeteners should be taken in moderation. Physical activity, along with a healthy diet is still the best way available to reduce weight as well as caloric intake. If you find it hard to fight sweet cravings, you may notice that it is only hard in the very beginning. If you go cold turkey on sugar entirely (including artificial or even natural sweeteners), you may notice that very soon your cravings disappear altogether, and you will find enjoyment in other types of foods rather than sweet foods. This can go a long way in helping you maintain a healthy diet, controlling weight and blood sugar, as well as mood swings.

If you are suffering from diabetes-related neuropathy, please check out this Guide by Dr. Randall C. Labrum, Clinician, Researcher and Author. It has helped a lot of people end chronic peripheral neuropathy and regain health and well-being.

“I get so excited every time I have the opportunity to help someone with a chronic unresolved health problem. The ability to provide my expertise and experience in resolving these conditions creates a feeling of satisfaction like nothing else.”
Dr. Randall C. Labrum, Clinician, Researcher and Author

 

DIABETES AND INSOMNIA

Relationship Between Diabetes and Insomnia

Diabetes and Insomnia – Are They Linked?

Whether diabetes and insomnia are linked and if so, in which ways exactly, has been one question that has caused countless debates among medical experts. Although plenty of evidence has shown that insomnia often occurs in diabetic patients,  the possibility of insomnia actually causing diabetes in healthy individuals still remains a question.

The Journal of Clinical Endocrinology published a study showing findings that may surprise you. Although the study conducted was relatively small compared to most of the available medical studies, it was still able to provide a relevant understanding of whether insomnia indeed can cause diabetes.

It has been found that interrupted or insufficient sleep in healthy individuals can affect the body’s ability to balance insulin, which may lead to insulin resistance, thus increasing chances of diabetes. A particularly alarming finding was that even a single night of lack of sleep could significantly increase the chances of diabetes in healthy subjects. Before you get worried, it needs to be said that the study was relatively small and not entirely representative. However, the finding definitely calls for further clinical research to reach a definite conclusion. Other studies have shown that diabetic patients’ condition worsens significantly when insomnia is present in their daily life. It becomes particularly bad if a person sleeps less than 6 hours per night. The lack of sleep seems to be able to majorly throw the body chemistry off and cause a whole host of consequences, not the last of which, especially for diabetics, is the blood sugar issues. It is yet unknown exactly why sleep has such a great influence on your body systems, but the effect is undeniably evident in multiple studies.

Studies have also shown links between obesity, another related factor to diabetes, and insomnia. This opens up another realm of discussion that explores the possibility of insomnia to indirectly cause diabetes in those individuals with weight issues.

One thing is definitely clear: insomnia makes any condition worse. Even completely healthy people feel off after a night of interrupted sleep. Insomnia becomes a real health hazard if it’s chronic, which often is the case in our over-scheduled, overly busy lives. Early work hours, parenting and lots of other life factors lead to interrupted or broken sleep that is never restored.

Insomnia can be present in various shapes and forms. It can be expressed in difficulty falling asleep, or broken sleep, when you seem to wake up in the middle of the night for no reason and then you are unable to go back to sleep. A lot of people, especially seniors, tend to wake up really early, before they are rested, and are unable to go back to bed. Insomnia, in general, seems to be particularly common among the elderly. It aggravates the health hazards of this already vulnerable population. As you may know, diabetes is also very common in the older population. This, combined with insomnia, can quickly wreak havoc in a  patient’s body, which is why it’s so important to try and curb insomnia, especially in older patients.

HOW TO KEEP INSOMNIA AT BAY

People most at risk of diabetic insomnia are the elderly and the people with weight management issues, particularly when the two are combined. Diabetes by itself can also aggravate insomnia through stress, medications, hormone fluctuations, pain, and discomfort. Although insomnia is almost never treated as a primary condition by itself, it is important, especially for diabetic patients, to take it as seriously as possible and take all measures to mitigate insomnia and its effects on your everyday life.

Most of the things you can do to help treat your insomnia are all related to improving your regime and overall health, as well as better sleep hygiene.

Create and maintain a routine around your sleep time. It could be a good idea to always go to bed at the same time so that your body knows when to produce more melatonin which will help you sleep. It is helpful to establish a set of relaxing, soothing activities before bed, such as a warm bath, a warm glass of decaffeinated tea or milk, or an hour with a good book in bed. Try to keep your environments dark and screen-free. Blue light from TV and phones is bad for melatonin production and has an invigorating effect on your brain which is the opposite of what you want in the evening. So try not to watch TV or read anything on your phone or tablet before going to bed, even though the temptation may be strong.

Avoid stimulants such as coffee or tea or drinks with excessive sugar. Don’t exercise or work before bed. Try to eliminate noise as well, as it can be stimulating. Keep devices, TV, and radio off.

Add a healthy exercise routine to your day. Vigorous exercising depletes excess energy, helps oxygenate your blood and releases endorphins. Together, these will help you achieve better relaxation at the end of the day.

Meditate. Meditation will help you calm your mind after the daily stresses and achieve deeper sleep faster.

If nothing else helps you maintain a healthier sleep routine, you may need to search for more comprehensive cures such as over the counter or prescription sleep aid. You may also consider homeopathic treatments like acupuncture. Definitely, consult your doctor about your insomnia concerns before you start any medications.

Suffering from insomnia disrupts a healthy lifestyle in diabetics as well as individuals not suffering from diabetes. If not treated, it can cause issues in the long run. Cure your sleep and you might notice a whole range of positive changes in your everyday life!

If you are suffering from diabetes-related neuropathy, please check out this Guide by Dr. Randall C. Labrum, Clinician, Researcher and Author. It has helped a lot of people end chronic peripheral neuropathy and regain health and well-being.

“I get so excited every time I have the opportunity to help someone with a chronic unresolved health problem. The ability to provide my expertise and experience in resolving these conditions creates a feeling of satisfaction like nothing else.”
Dr. Randall C. Labrum, Clinician, Researcher and Author

 

DIABETES RISK FACTORS

Diabetes Risk Factors That You Need To Watch For

9 Diabetes Risk Factors to be aware of

Type 2 Diabetes affects over 18 million Americans; this is a huge number that continues to increase, as diabetes becomes an epidemic of this day and age. A larger number of Americans are also affected with pre-diabetes, a condition that can easily turn into full-blown diabetes if not properly controlled. Diabetes does not only affect the United States but it also a common disease that affects people from different parts of the globe.

Diabetes commonly occurs in middle-aged to older adults since it is an adult-onset type of disease. However, more and more cases of children and adolescents who are overweight and living a sedentary lifestyle develop diabetes at an earlier age.

The following are 9 major risk factors for Type 2 Diabetes:

1. Age is a risk factor for diabetes. Unfortunately, statistics show that one in five people aged 65 and older have diabetes. Adults aged 45 years and older also have an increased risk of diabetes.

2. Body weight is a serious risk factor for diabetes. Individuals who are overweight, or who have a BMI index that is greater than 25 have a higher risk of diabetes at some point in their lives. More than eighty percent of those diagnosed with diabetes are overweight.

3. Excess fat in the stomach area. Even if you are generally not considered overweight, excess fat in the stomach area is linked to the body’s resistance to insulin, thus an increased risk of diabetes. Men who have the waist circumference greater than 40 inches and women who have the waist circumference greater than 35 inches have excess fat in their stomach area and have increased risks.

4. Genetics and family history. If your family has a history of diabetes then there is also a high chance that you might develop the disease too. The risk factor increases the closer your relation to the family member with diabetes is.

5. Ethnicity is a factor. Your ethnic background is also a factor that affects your chances of diabetes. American Indians, African Americans, Latinos, Pacific Islanders, and Asian Americans are two and half times more prone to acquiring diabetes than Caucasians.

6. Gestational Diabetes. Mothers who were diagnosed with gestational diabetes also increase their risk of diabetes in the future. Mothers who had gestational diabetes tend to give birth to larger babies, sometimes weighing more than nine pounds. This diabetic condition occurs during the latter stages of pregnancy and goes away after birth.

7. Low levels of good cholesterol and triglycerides. Low levels of HDL (35 or lower) or low triglyceride levels (150 or higher) indicate that the body does not properly respond to insulin. This condition is known as insulin resistance, which increases the risks of diabetes.

8. High blood pressure. If your blood pressure is 140/90 or even higher, you have an increased risk of diabetes. Having high blood pressure is closely linked to insulin resistance.

9. Low activity and sedentary lifestyle. Living a sedentary lifestyle will also increase your chances of diabetes as it impairs the natural ability of the cells in your body to remove sugar present in your blood. Not being able to regularly exercise at least three times a week is considered a sedentary lifestyle.

PRE-DIABETES

Another risk factor for diabetes is if you already have pre-diabetes. Pre-diabetes occurs when your body starts either producing less insulin or cannot effectively use produced insulin to transport glucose. Although pre-diabetes is reversible, without proper measures it will with time develop into full-blown diabetes. While no one knows what exactly causes pre-diabetes, it is evident that there are certain risk factors that are present in most cases of pre-diabetes occurrence. Such risk factors are being overweight, sedentary lifestyle and not enough exercise, being over 45 years old and having gestational diabetes.

Pre-diabetes usually has no tell-tale symptoms. A person with pre-diabetes may be hungry a lot of the times but still be losing weight instead of gaining. Another possible sign is increased thirst and increased urination. However, a majority of individuals who have pre-diabetes are not aware of their condition. Often that condition is left unchecked and they will likely develop full-blown Type 2 Diabetes. If you have pre-diabetes, it is important to take the necessary actions as soon as possible as it can be prevented. The following signs might help you determine whether you at risk of pre-diabetes or diabetes:

  • Being overweight or obese
  • Feeling  numbness in your legs or feet
  • Itching on your genital area
  • Blurred vision
  • Development of heart disease
  • Slow regeneration of damaged skin and gums
  • Urinary infections
  • Frequent feeling of thirst and the need to urinate

If you are experiencing any of these symptoms, it is advised that you get yourself checked to be sure. Even though these symptoms may be indicative of other conditions, it really doesn’t hurt to make sure. If you find out about your condition early enough, you will be able to take immediate and effective action to control pre-diabetes and find the best lifestyle modifications for you to be able to reverse it.